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Chemistry & Biochemistry

Jimmy Franco, Ph.D.

Associate Professor

Chemistry and Biochemistry

Jimmy Franco’s teaching responsibilities are in biochemistry and organic chemistry. His research focuses on the interface of organic chemistry and biochemistry. The emphasis of his research is on drug discovery, continuing his collaboration with colleagues at the University of Toledo.

Degree(s)

Ph.D., Chemistry, University of California, Davis
B.S., Chemistry, Beloit College

Teaching

  • Biochemistry ( CHM30370)
  • Organic Chemistry Laboratory (CHM2210L)
  • Chemistry for the Health Professionals (CHM1220)
  • Honors Senior Capstone Workshop (HON4001H)

Research

Jimmy Franco’s research interests are in identifying novel chemical therapeutics to treat neglected diseases, such as tuberculosis. He uses computational methods to more efficiently identify biologically active compounds. Franco’s research group also develops new chemical methodology, which enables them to more efficiently synthesize biologically relevant compounds. They are also developing novel pedagogical methods to enhance the learning experience for the next generation of students. 

Publications

Franco J., Blackie, M., Toth, D., Smith, P., Capuano, J., Fastnacht, K., Berkes, C., A structural comparative approach to identifying novel antimalarial compounds Comp. Bio.  Chem. In Press, Accepted, avaible online May 2, 2013

Pinault L, Han JS, Kang CM, Franco J, Ronning D., Zarfirlukast inhibits Complexation of Lsr2 with DNA and Growth of Mycobacterium tuberculosis; Antimicrob Agents Chemother. 2013 May;57(5):2134-40. doi: 10.1128/AAC.02407-12. Epub 2013 Feb 25

Toth, D and Franco, J; Using Supercomputing to Conduct Virtual Screen as Part of the Drug Discovery Process in a Medicinal Chemistry Course;  J. Comp.Sci. Ed 2012, 3 (2) pp 18-25

Franco, J; Online Gaming for Understanding Folding, Interactions, and Structure; J. Chem. Educ.,201289 (12), pp 1543–1546doi.org/10.1021/ed200803e

Franco, J., Hammons, J., Olmstead, M. Rios, D.; New Tetraazaannulene Host  for Fullerenes; Inorg. Chem2010

Franco, J.,Ell, J., Hilton, A., Hammons, J., Olmstead, M., C60Br8and C60(NO2)6as Selective Tools in Organic Synthesis; Fullerenes, Nanotubes and CarbonNanostructures,2009,17, 349-360

Franco, J., Hammons, J., Olmstead, M.,Bis[1-(1-damantyliminomethyl)-2-naphtholato-κ2N,O]cobalt(II) Acta Crys., Section E: Structure ReportsOnline 2008, E64(10)

Franco, J., Hammons, J., Olmstead, M.; Tetra- 2-acetato- 8O:O’-bis{[1-(1-adamantyliminiomethyl)-2-naphtholato- O]rhodium(II)}; Acta Cryst. 2007, E63,m2606-m2607.

Contact

978-837-5285
francoj@merrimack.edu

Office

Mendel 323