Assistant Professor, Chemistry and Biochemistry
My laboratory research focuses on studying the interactions between nanoparticles and biomolecules, including proteins, DNA and small molecules. Current projects include developing a method to quantify the number of proteins bound to each nanoparticle, and determining the cellular proteins targeted by nanoparticles of varied core sizes and charges. In this work, my students and I use a variety of analytical instrumentation and molecular biology methods, including ultraviolet-visible spectroscopy, transmission electron microscopy, fluorescence spectroscopy, electrophoresis, NMR spectroscopy, gas phase mass spectrometry and liquid phase mass spectrometry. Teaching interests include developing guided inquiry activities for the general chemistry lab, and experiments focused on polymers and nano-materials for introductory and advanced courses.
Truong, L.; Zaikova, T.; Baldock, B.L.; Balik-Meisner, M.; To, K.; Reif, D.M.; Kennedy, Z.C.; Hutchison, J.E.; Tanguay, R.L. “Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish,” Nanotox. 2019, published online 02 April 2019.
Baldock, B.L.; Hutchison, J.E. “UV-Visible Spectroscopy-based Quantification of Unlabeled DNA Bound to Gold Nanoparticles.” Analytical Chemistry, 2016, 88 (24), 12072-12080.
Baldock, B.L.; Exton, D. B.CH 6. “Determination of the Heat Exchanged in Chemical Reactions,” Hayden McNeil LLC, 2016, 2017, University of Oregon Department of Chemistry and Biochemistry “Experiments in General Chemistry” p. 39-46.
Baldock, B.L.; Exton, D. B. CH 6. “Determination of the Heat Exchanged in Chemical Reactions,” McGraw-Hill Education, 2014, 2015, University of Oregon CH 227 General Chemistry Laboratory Manual p. 65-69.
